Truveta brand logo mark in teal on a black background, featuring stacked chevron shapes forming the Truveta symbol.

Therapeutic area

Metabolic diseases and endocrinology

How can we help?

39M+

patients with metabolic disease

13.5M+

type 2 diabetes

745K+

type 1 diabetes

13.4M+

obesity

7M+

hypothyroidism

300K+

Metabolic dysfunction-associated steatotic liver disease (MASLD) and steatohepatitis
(MASH)

917K+

polyendocrine metabolic ovarian syndrome (PMOS)

Study metabolic disease with comprehensive clinical context

Go beyond diagnoses and billing codes with clinically rich data that captures:

Disease severity and progression

  • Laboratory markers of disease including: HbA1c, glucose trends, renal and liver function
  • Weight and BMI
  • Liver stiffness and fibrosis staging

Therapies and treatment response

  • GLP-1s, SGLT2s, insulin and emerging therapies for metabolic disease
  • Treatment persistence, switching, and utilization patterns
  • Surgical interventions
  • CGM and insulin pump use

Social, behavioral, and familial risk factors

  • Social determinants of health (SDOH)
  • Behavioral and lifestyle factors
  • Family history
  • Genetic testing and inherited metabolic disorders

Disease severity and progression

Therapies and treatment response

Social, behavioral, and familial risk factors

Disease characterization

Laboratory markers of disease, including HbA1c, glucose trends, renal and liver function
Weight and BMI
Liver stiffness and fibrosis staging

Therapies and treatment response

GLP-1 RAs, SGLT2 inhibitors, insulin, and emerging therapies for metabolic disease
Treatment persistence, switching, and utilization patterns
Surgical interventions
CGM and insulin pump use

Social, behavior, and familial risk factors

Social determinants of health (SDOH)
Behavioral and lifestyle factors
Family history
Genetic testing and inherited metabolic disorders

Understand metabolic disease through rich clinical context

Truveta brings extraordinary clinical depth to metabolic disease research, capturing regulatory-grade, validated variables from clinical notes—including disease severity, treatment rationale, pathology findings, fibrosis staging, and reasons for treatment discontinuation.

Integrated with structured EHR data, laboratory results, imaging, medications, and claims, these research-ready variables enable precise study of treatment response, disease progression, and rare metabolic conditions.

Identify patients who discontinue treatment because of cost using validated variables derived from clinical notes, not just structured EHR fields or medication records.

See the entire metabolic disease journey with multimodal data

Connect biomarkers, medications, imaging, and clinical context across the patient journey. Enable deeper analysis of disease progression, treatment response, and outcomes using longitudinal data from:

Stacked area chart showing cumulative GLP-1 receptor agonist prescribing rates from 2019 through June 2026 by medication and indication, with tirzepatide accounting for a growing share of prescriptions.

Longitudinal prescribing data enables researchers to study therapy adoption, persistence, and real-world treatment patterns across the evolving metabolic disease landscape.

Laboratory results and biomarkers
Medical imaging and radiology reports
Clinical notes and pathology findings
Medication prescribing and dispensing
Claims, mortality, and mother-child linked data

From foundational research to regulatory and clinical impact

AI training

Develop AI multimodal models using longitudinal metabolic and endocrine data, including labs, medications, vitals, and clinical notes to predict disease progression and treatment response

Clinical trials

Accelerate trial timelines and identify eligible patients faster with precise metabolic phenotypes

Therapy adoption

Optimize commercial performance by tracking utilization, persistence, switching, and prescribing trends in real time

Safety

Save on costly post-marketing studies and detect metabolic complications and treatment-related risks earlier

Outcomes research

Develop novel research and evaluate clinical and economic outcomes using more granular clinical data