Resources

Whitepapers

Data quality

Truveta Data comprises billions of EHR data points, representing more than 120 million patient journeys from more than 20,000 clinics and 900 hospitals, updated daily. Truveta Data adheres to the highest standards of quality and provenance, supported by stringent quality control processes detailed in this whitepaper.

Truveta Language Model

Advancements in AI have presented a unique opportunity to transform and clean massive streams of healthcare data to make it available for research, innovation, and patient care. This whitepaper explains the Truveta Language Model, a large-language model used to clean billions of EHR data points for health research.

Data analytics

The pace of research-driven medical progress has been slowed by difficulties in obtaining, cleaning, and analyzing clinical data. Truveta Studio addresses these challenges by empowering researchers with immediate access to Truveta Data, powerful analytics and AI, and the ability to generate evidence for regulatory submissions. This whitepaper explains our approach to analytics.

Data security

Truveta’s advanced security systems protect Truveta Data through every stage of the data handling process and have been validated to meet the most rigorous standards for privacy and security. This whitepaper outlines how we manage the complex flow of health data to maintain customer and member health system trust.

Patient privacy

Founded by health systems, Truveta has a deep commitment to patient privacy. This whitepaper outlines how data flows from our health system members from the Truveta platform and the advanced measures taken to ensure patient privacy and protect against potential reidentification.

Powering device research

Medical device companies are challenged by a significant lack of real-world data on device use in clinical practice. In this whitepaper, learn how Truveta provides critical device specific information linked to deep clinical data to accelerate device research for over 150,000 unique medical devices.

Advancing cardiovascular research

Cardiovascular disease is a leading cause of death in the US, but researchers face many challenges when seeking to study the safety and effectiveness of drugs and devices used to treat it. This whitepaper highlights historical limitations of RWD and explains how Truveta addresses them to accelerate research on outcomes and care.

Truveta Mapper: A zero-shot ontology alignment framework

We share the technical details behind Truveta Mapper the underlying AI technology in the Truveta Language Model. Truveta Mapper leverages a multi-task sequence-to-sequence transformer model to perform alignment across multiple ontologies in a zero-shot, unified, and end-to-end manner. This paper was originally published at arXiv.

Ethics policy

We believe it is a moral imperative to harness the power of data to improve healthcare. We know we’ve taken on an enormous responsibility, and we pursue our work with a commitment to patient privacy, broadly enabling research and transparency about our data, all in close coordination with our member health systems.

Briefings & case studies

How real-world data is transforming GLP-1 research for diabetes and obesity care

GLP-1 medications are revolutionizing the way we treat type 2 diabetes and obesity. With Truveta Data, researchers gain access to RWD that provides comprehensive insights, addressing critical questions about the real-world performance of GLP-1 therapies.

Briefing

Transform the future of knee, hip, and shoulder replacements with device-level data

Standard outcomes data often limits orthopedic research to broad insights, such as overall success rates, average recovery times, or general complication rates. With Truveta, orthopedic researchers can access device-level insights and patient-reported outcomes from the most complete, timely, and clean regulatory-grade EHR data available.

Briefing

10 reasons to choose Truveta’s mother-child EHR dataset

Understanding the link between maternal health and child outcomes is crucial for advancing both maternal and pediatric care. Truveta’s dataset includes daily updated data from over 1 million mother-child pairs, providing critical insights into how maternal health, behaviors, and exposures influence child outcomes.

Briefing

Heart failure innovation

The lack of treatment evolution for heart failure (HF) is partly due to the difficulty and cost of studying complex inpatient interventions. This case study highlights how Reprieve Cardiovascular, a clinical-stage startup focused on decongestion for HF, partnered with Truveta to understand the current standard of care for HF to de-risk their pivotal clinical study and optimize trial protocols.

Case study

Psoriasis data

Psoriasis is chronic, systemic disease that affects over 8 million people in the United States. Truveta’s complete, timely and clean EHR data includes a psoriasis patient population with over 4.3 million relevant notes. This briefing highlights the possibilities for psoriasis research with robust EHR data.

Briefing

RWE for regulatory submissions

The FDA supports using real-world evidence for regulatory decision-making but stipulates that the underlying data must be fit for purpose. This briefing highlights Truveta’s approach to ensuring high-quality, fit-for-purpose EHR data and streamlining real-world evidence submissions to regulatory authorities.

Briefing

Prostate cancer data

One in 8 men will develop prostate cancer, yet real-world datasets often fail to capture the full prostate cancer patient journey, early-stage treatments, and all treatment modalities. Truveta’s complete, longitudinal EHR data spans care settings and treatment types. This briefing highlights data available to support prostate cancer research and innovation.
Briefing

Medical images

De-identified medical images are often hard to find and detached from clinical context, hindering research efforts. Truveta provides access to more than 85 million medical imaging studies integrated with complete EHR data. This briefing provides insight into the images available and how they’re advancing research.

Briefing

Assessing device safety

Despite promising clinical data for novel pulmonary embolism therapies, there are no randomized prospective studies comparing them and guidelines have not been updated to reflect real-world safety data. This case study showcases findings from a peer-reviewed study using Truveta Data to compare the safety of devices from Boston Scientific and Inari Medical.

Case study

Why TLM outperforms other LLMs

Unlocking the full potential of healthcare data has long been hindered by issues of fragmentation and lack of structure. The Truveta Language Model (TLM) offers a premier solution for normalizing EHR data at scale, enabling novel research. This briefing highlights what sets TLM apart from general large language models.

Briefing

Linked EHR-SDOH data

Clinical care affects only 10-20% of modifiable health factors, while 80-90% are influenced by behaviors, socioeconomic factors, and the environment. This briefing highlights how integrating social drivers of health (SDOH) data into real-world data analyses offers precise insights on unmet needs, healthcare disparities, and therapy performance.

Briefing

Echo data

Echocardiograms contain crucial clinical observations relevant for cardiovascular research, but obtaining these measures at scale for real-world data analysis has been a longstanding challenge. This briefing highlights how Truveta is normalizing and extracting echo observations at scale for research, and outlines data availability for specific measures.

Briefing
Insights from real-time EHR data

Timeliness

Timely data are critical for life sciences and healthcare organizations, enabling innovation and high-quality patient care. However, most RWD sources have lags of weeks to months. This briefing focuses on Truveta’s real-time data and showcases the clinical questions it enables researchers to answer.

Briefing
Tracking GLP-1 prescribing trends

GLP-1 prescribing

GLP-1s, originally created to treat diabetes, have been found to suppress appetites and induce substantial weight loss in many patients. Extensive media coverage and celebrity endorsements have created overwhelming demand for these drugs, but little is known about real-world use. This briefing highlights findings from an analysis of first-time GLP-1 prescribing trends.

Briefing

PAD treatment

Peripheral Artery Disease (PAD) is a common disease that causes the narrowing of the arteries in the extremities. As part of PAD Awareness month, Truveta Research investigated disparities in the frequency of common procedures used to treat PAD, known as endovascular (or minimally invasive) revascularization, and the associated outcomes.

Briefing

Webinars

Raising the bar on real-world data quality: ensuring regulatory-grade EHR data

Learn why researchers are betting on EHR data as the future of real-world evidence generation and what to look for when evaluating the quality of a real-world dataset.

Webinar

Uncovering disparities in access to popular treatments: insights from linked EHR and SDOH data

Explore how linked EHR and SDOH data are accelerating the identification of health disparities for type 2 diabetes, Alzheimer’s disease, and heart disease treatments

Webinar

Enabling timely comparative effectiveness research: head-to-head analysis of GLP-1s for weight loss

See the results of a real-world GLP-1 comparative effectiveness study and the impact of timely and representative RWD in assessing performance of new therapies.

Webinar

Driving therapeutic innovation and de-risking clinical development: The power of RWD from EHRs

Speakers from Truveta, Reprieve Cardiovascular, The Permanente Medical Group, and Stanford Cardiovascular Medicine discuss how Truveta Data is being used to drive product innovation for acute heart failure.

Webinar

Transforming clinical research: Scaling real-world data across diseases with expert-led AI

Hear from experts at UCB and Truveta as they demonstrate the power of Truveta’s AI-driven extraction of critical information from free text clinical notes to further research at UCB.

Webinar

Advancing clinical research through unprecedented data and learning community for health

Partnering with Fierce Pharma, hear from an expert panel on the power of unprecedented data and what early patient insights have been unveiled.

Webinar

Videos

Terry Myerson Truveta CEO introduces the Truveta Platform

Introducing Truveta Studio: Delivering the health data and analytics the world deserves now

Terry Myerson Truveta CEO introduces the Truveta Platform

Truveta announces collaboration with Boston Scientific

Terry Myerson Truveta CEO introduces the Truveta Platform

Empowering researchers with Truveta Studio

An image of all of the Truveta health system members' logos

Health system leaders form Truveta to save lives with data

Terry Myerson Truveta CEO introduces the Truveta Platform

Helping address health inequities with data

Terry Myerson Truveta CEO introduces the Truveta Platform

The importance of data quality for medical research

An image of all of the Truveta health system members' logos

Truveta and LexisNexis Risk Solutions partner to improve data quality and health equity

Terry Myerson Truveta CEO introduces the Truveta Platform

Introducing the Truveta platform and new COVID-19 insights

Terry Myerson Truveta CEO introduces the Truveta Platform

Microsoft and Truveta announce strategic partnership to achieve our vision of Saving Lives with Data

Terry Myerson Truveta CEO introduces the Truveta Platform

Terry Myerson keynote at ViVE 2022

Featured research

A time-series analysis of anxiety diagnoses and prescriptions from January 2018 to January 2023

medRxiv

https://doi.org/10.1101/2023.12.21.23300415

Time-series analysis of first-time pediatric speech delays from 2018 to 2022

JAMA Pediatrics

doi:10.1001/jamapediatrics.2023.5226

Percentage change in body weight for those taking tirzepatide (Mounjaro) versus semaglutide (Ozempic) for those with overweight or obesity

Comparative effectiveness of semaglutide and tirzepatide for weight loss in adults with overweight and obesity in the US: A real-world evidence study

medRxiv

doi: https://doi.org/10.1101/2023.05.18.23290122