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GLP-1 RA prescription trends: January 2018 – September 2025

GLP-1 RA prescription trends: January 2018 – September 2025

by Truveta Research | Oct 20, 2025 | Featured research, Research, Research Insights

Overall GLP-1 prescribing rates (GLP-1 RA prescriptions per total prescriptions) in September 2025 remained stable relative to June 2025 (+4.6%). As of September 2025, GLP-1 prescriptions account for 6.5 out of every 100 prescriptions in the US. Tirzepatide continues...
Associations of nutrition counseling, insulin, and metformin therapy with post-GTT weight gain in a large pregnancy cohort

Associations of nutrition counseling, insulin, and metformin therapy with post-GTT weight gain in a large pregnancy cohort

by Truveta Research | Oct 17, 2025 | Research, Research Insights

Nearly half of patients with gestational diabetes mellitus (GDM) received nutrition counseling within 45 days of diagnosis, while smaller proportions initiated insulin (15%) or metformin (10%). Despite being the first-line intervention, about half of patients with GDM...
Real-world patterns of glucose tolerance testing and gestational diabetes in pregnancy

Real-world patterns of glucose tolerance testing and gestational diabetes in pregnancy

by Truveta Research | Oct 17, 2025 | Research, Research Insights

Nearly one-quarter of patients exceeded the 140 mg/dL threshold on the 1-hour glucose tolerance test. However, about 1 in 10 patients with elevated values did not receive recommended follow-up testing or a GDM diagnosis, highlighting gaps in adherence to clinical...
Exploring gestational weight gain and newborn birth weight

Exploring gestational weight gain and newborn birth weight

by Truveta Research | Oct 2, 2025 | Research, Research Insights

Mothers who gained more weight during pregnancy had heavier infants and mothers who lost weight during pregnancy had lighter infants. Mothers who gained less weight (particularly <15 pounds) and who lost weight during their pregnancy had increased risk of a...
Exploring gestational weight gain and loss

Exploring gestational weight gain and loss

by Truveta Research | Oct 2, 2025 | Research, Research Insights

Across their pregnancies, mothers had an average of 12 weight measurements, allowing us to construct a longitudinal ‘journey’ of their weight change. Mothers gained an average of 31 pounds across their pregnancies and 45% of mothers had evidence of some weight loss....
Impact of the CVS GLP-1 formulary change: Trends in switching

Impact of the CVS GLP-1 formulary change: Trends in switching

by Truveta Research | Sep 5, 2025 | Research, Research Insights

In July 2025, following the CVS formulary change, 9.6% of patients on AOM tirzepatide switched to a different drug. This was more than a 16-fold increase compared with the average earlier in the year. Among AOM tirzepatide users who switched to a different GLP-1...
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